What are the agents associated with pain of a bee sting?


The agents associated with pain and inflammation of a bee sting include:
1 histamine
2 apamin
3 hyaluronidase

ONE or MORE of the responses above is (are) correct. Decide which of the responses is
(are) correct. Then choose:
A if 1, 2 and 3 are correct
B if 1 and 2 only are correct
C if 2 and 3 only are correct
D if 1 only is correct
E if 3 only is correct


  1. A is the answer and Maryam is the winner.
    The pain and inflammation associated with a bee sting are caused by agents
    that include histamine, apamin, which is neurotoxic, and the enzyme
    hyaluronidase, which breaks down the intercellular tissue structure, promoting
    the penetration of the venom into the human tissues.