Inflammatory mediators that are released in an asthmatic attack include?

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1     histamine

2     leukotrienes

3     prostaglandins

 

A     1, 2, 3

B     1, 2 only

C     2, 3 only

D     1 only

E     3 only

5 COMMENTS

  1. A is the answer and the winners are Clement and Area.
    Details below:
    In an acute attack there is an increase of eosinophils in the bronchial epi-
    thelium releasing proteins and neurotoxins which damage the epithelium. In
    addition inflammatory cells such as mast cells and basophils release spasmo-
    gens such as histamine, leukotrienes, prostaglandins, thromboxane and
    platelet-activating factor. These result in bronchospasm and oedema, inflam-
    mation and airway hyperactivitiy.

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