Marijuana in Pregnancy Links to Sleep Problems in Children


A new study conducted by researchers from University of Colorado Boulder has just shown taking marijuana while pregnant could increase the chances of children developing childhood sleep problems.

The study published in Sleep Health: The Journal of The National Sleep Foundation, links prenatal cannabis use to developmental problems in children and the first to suggest it may impact sleep cycles long-term.

John Hewitt, director of the Institute for Behavioural Genetics at CU Boulder said: “As a society, it took us a while to understand that smoking and drinking alcohol are not advisable during pregnancy, but it is now seen as common sense.”

For the study, Hewitt and lead author Evan Winiger analysed baseline data from the landmark Adolescent Brain and Cognitive Development (ABCD) study, which is following 11,875 youth from age 9 or 10 into early adulthood.

Marijuana in Pregnancy Links to Sleep Problems in Children

As part of an exhaustive questionnaire upon intake, participants’ mothers were asked if they had ever used marijuana while pregnant and how frequently. (The study did not assess whether they used edibles or smoked pot). The mothers were also asked to fill out a survey regarding their child’s sleep patterns, assessing 26 different items ranging from how easily they fell asleep and how long they slept to whether they snored or woke up frequently in the night and how sleepy they were during the day.

About 700 moms reported using marijuana while pregnant. Of those, 184 used it daily and 262 used twice or more daily.

After controlling for a host of other factors, including the mother’s education, parent marital status and family income and race, a clear pattern emerged.

“Mothers who said they had used cannabis while pregnant were significantly more likely to report their children having clinical sleep problems,” said Winiger, a graduate student in the Department of Psychology and Neuroscience.

Those who used marijuana frequently were more likely to report somnolence symptoms (symptoms of excess sleepiness) in their children, such as trouble waking in the morning and being excessively tired during the day.

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The authors noted that, while their sample size is large, the study has some limitations.

“We are asking mothers to remember if they smoked marijuana 10 years ago and to admit to a behaviour that is frowned upon,” said Winiger, suggesting actual rates of prenatal use may have been higher.

While the study doesn’t prove that using cannabis while pregnant causes sleep problems, it builds on a small but growing body of evidence pointing to a link.

For instance, one small study found that children who had been exposed to marijuana in-utero woke up more in the night and had lower sleep quality at age 3. Another found that prenatal cannabis use impacted sleep in infancy.

And, in other previous work, Hewitt, Winiger and colleagues found that teenagers who frequently smoked marijuana were more likely to develop insomnia in adulthood.

Researchers aren’t sure exactly how cannabis exposure during vulnerable developmental times might shape future sleep.

But studies in animals suggest that tetrahydrocannabinol (THC) and other so-called cannabinoids, the active ingredients in pot, attach to CB1 receptors in the developing brain, influencing regions that regulate sleep. The ABCD study, which is taking frequent brain scans of participants as they age, should provide more answers, they said.

Meantime, mothers-to-be should be wary of dispensaries billing weed as an antidote for morning sickness. According to CU research, about 70 per cent of Colorado dispensaries recommend it for that use.

But mounting evidence points to potential harms, including low birth weight and later cognitive problems. With marijuana in the market today including far higher THC levels than it did a decade ago, its impacts on the fatal brain are likely more profound than they once were.

“This study is one more example of why pregnant women are advised to avoid substance use, including cannabis,” said Hewitt. “For their children, it could have long-term consequences.”

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