What do you know about Perindopril?


1     may lead to deterioration of glucose tolerance

2     dose in GX should be reviewed due to under-dosing

3     treatment warrants routine renal function tests to be undertaken


A    1, 2, 3

B    1, 2 only

C    2, 3 only

D    1 only

E    3 only


  1. E is the answer and there is no winner for the his question.
    Details Below:
    An advantage of angiotensin-converting enzyme (ACE) inhibitors such as
    perindopril is that they do not interfere with glucose tolerance and they can
    be used as antihypertensive agents or for the management of heart failure in
    diabetic patients. A maximum daily dose of 8 mg of perindopril may be recom-
    mended. Deterioration in renal function, which can be monitored by
    measuring blood urea and creatinine concentrations, may occur, especially in
    patients who have existing kidney disease and heart failure. Monitoring
    parameters to be measured in GX should include renal function.